DNA methylation is critical for tooth agenesis: implications for sporadic non-syndromic anodontia and hypodontia
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چکیده
منابع مشابه
DNA methylation is critical for tooth agenesis: implications for sporadic non-syndromic anodontia and hypodontia
Hypodontia is caused by interactions among genetic, epigenetic, and environmental factors during tooth development, but the actual mechanism is unknown. DNA methylation now appears to play a significant role in abnormal developments, flawed phenotypes, and acquired diseases. Methylated DNA immunoprecipitation (MeDIP) has been developed as a new method of scanning large-scale DNA-methylation pro...
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Congenital Tooth Agenesis or Hypodontia is one of the most common developmental anomaly of the human dentition, presents itself with one or more missing teeth. It is a polygenetic disorder that can occur either in isolation or as a co-finding in many syndromes. The Clinical features, diagnostic characteristics and management strategies all depend on the severity of the condition, presence or ab...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep19162